Is Interferon Used For Cancer?

Is Interferon the same as chemotherapy?

Interferon-alfa2b is different than a chemotherapy drug; it is actually a natural part of your body’s immune system.

It is known as a cytokine, which are chemicals normally secreted by cells called leukocytes in response to a virus, bacteria, or other foreign intruders..

What does interferon treat?

This medication is used to treat various cancers (e.g., leukemia, melanoma, AIDS-related Kaposi’s sarcoma). It is also used to treat virus infections (e.g., chronic hepatitis B, chronic hepatitis C, condylomata acuminata). This medication is the same as a protein that your body naturally produces (interferon).

Can interferon cause cancer?

According to the Toronto team, the risk for subsequently developing liver cancer among participants who received interferon therapy and who were cured decreased by 76%.

How long can you take interferon?

Why interferons cause long-term side effects Interferon treatment for hepatitis C would typically last 24–48 weeks (6–12 months). Interferons caused many long-term side effects partly because of this long treatment time. Using the drug for this length of time gave side effects a chance to develop and get worse.

Does interferon kill viruses?

Interferons do not directly kill viral or cancerous cells; they boost the immune system response and reduce the growth of cancer cells by regulating the action of several genes that control the secretion of numerous cellular proteins that affect growth.

Is interferon an antiviral?

The interferons (IFNs) are glycoproteins with strong antiviral activities that represent one of the first lines of host defense against invading pathogens. These proteins are classified into three groups, Type I, II and III IFNs, based on the structure of their receptors on the cell surface.

What does interferon mean?

Interferons (IFNs, /ˌɪntərˈfɪərɒn/) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.

How much does interferon cost?

The high cost of interferon and ribavirin treatment—approximately $30,000 for 48 weeks—would need to be added to either treatment. (Ribavirin is a pill available under various brand names. Pegylated interferon is sold under several brand names and is injected, typically by the patient.)

Where does interferon come from?

Type I interferon (IFN-alpha and IFN-beta) is secreted by virus-infected cells while type II, immune or gamma interferon (IFN-gamma) is mainly secreted by T cells, natural killer (NK) cells and macrophages.

Does Interferon suppresses the immune system?

Interferons are man-made versions of proteins your body makes. These drugs work with your immune system to help it find and attack viruses and cancer. They can stop virus and cancer cells from growing and spreading, and prevent other cells from getting infected.

Can Interferon be taken orally?

Interferon-alpha (IFN-alpha) given orally has biological activity in humans and other animals. The dose providing the most benefit delivers IFN-alpha to the oral mucosa in a concentration (10(2)-10(3) IU), similar to that naturally produced in the nasal secretions during respiratory infections.

Is interferon toxic?

Results: Adverse effects due to IFN-alpha have been described in almost every organ system. Many side-effects are clearly dose-dependent. Taken together, occurrence of flu-like symptoms, hematological toxicity, elevated transaminases, nausea, fatigue, and psychiatric sequelae are the most frequently encountered.