Quick Answer: How Does Interferon Treatment Work?

What is the drug interferon used for?

This medication is used to treat various cancers (e.g., leukemia, melanoma, AIDS-related Kaposi’s sarcoma).

It is also used to treat virus infections (e.g., chronic hepatitis B, chronic hepatitis C, condylomata acuminata).

This medication is the same as a protein that your body naturally produces (interferon)..

How do interferons protect the body against viruses?

Via interferons Virally infected cells produce and release small proteins called interferons, which play a role in immune protection against viruses. Interferons prevent replication of viruses, by directly interfering with their ability to replicate within an infected cell.

Is interferon an antiviral?

The interferons (IFNs) are glycoproteins with strong antiviral activities that represent one of the first lines of host defense against invading pathogens. These proteins are classified into three groups, Type I, II and III IFNs, based on the structure of their receptors on the cell surface.

Does interferon cause depression?

Interferon alpha (IFN-α)-treated patients commonly develop depression during the therapy period. Although most IFN-α-induced depressive disorders achieve remission after IFN-α therapy, no studies have examined the long-term mood effects of IFN-α treatment.

What does interferon mean?

Interferons (IFNs, /ˌɪntərˈfɪərɒn/) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.

What is interferon antiviral response?

Interferons provide a first line of defence against virus infections by generating an intracellular environment that restricts virus replication and signals the presence of a viral pathogen to the adaptive arm of the immune response.

How long does it take for interferon to work?

Occurs within 1-2 hours of treatment, may last up to 24 hours (over time the intensity of these symptoms decreases depending on the dose, how it is given, and the schedule of administration). Fatigue , drowsiness. Low blood counts . Your white and red blood cells and platelets may temporarily decrease.

How long can you take interferon?

Why interferons cause long-term side effects Interferon treatment for hepatitis C would typically last 24–48 weeks (6–12 months). Interferons caused many long-term side effects partly because of this long treatment time. Using the drug for this length of time gave side effects a chance to develop and get worse.

How much does interferon cost?

The high cost of interferon and ribavirin treatment—approximately $30,000 for 48 weeks—would need to be added to either treatment. (Ribavirin is a pill available under various brand names. Pegylated interferon is sold under several brand names and is injected, typically by the patient.)

What is the antiviral state?

The antiviral state is the result of a signaling pathway induced by IFN-alpha or IFN-beta following viral infection. It leads to the transcription of various cellular antiviral genes coding for host defense proteins.

Does interferon kill viruses?

Interferon is secreted by cells in response to stimulation by a virus or other foreign substance, but it does not directly inhibit the virus’s multiplication. Rather, it stimulates the infected cells and those nearby to produce proteins that prevent the virus from replicating within them.