Quick Answer: How Is Infective Endocarditis Treated?

What happens when you have endocarditis?

In endocarditis, clumps made of germs and cell pieces form an abnormal mass in your heart.

These clumps, called vegetations, can break loose and travel to your brain, lungs, abdominal organs, kidneys, or arms and legs..

Can symptoms of endocarditis come and go?

Infective endocarditis symptoms may progress slowly or come on suddenly. Sometimes symptoms come and go. Other signs and symptoms of infective endocarditis include: Fatigue or weakness.

Can you have endocarditis without fever?

Isolated mitral posteromedial papillary endocarditis is a rare entity and highlights that even without fever, murmurs, or constitutional symptoms, severe multisystem infections from endocarditis can occur.

What valve is affected by endocarditis?

The tricuspid valve is most commonly affected (50%), whereas involvement of the mitral and aortic valves is less common (20% each). The involvement of multiple valves is common. Pulmonary valve endocarditis is rare.

What is the treatment for infective endocarditis?

Initial empiric therapy in patients with suspected endocarditis should include vancomycin or ampicillin/sulbactam (Unasyn) plus an aminoglycoside (plus rifampin in patients with prosthetic valves). Valve replacement should be considered in selected patients with infectious endocarditis.

How quickly does endocarditis develop?

There are two forms of infective endocarditis, also known as IE: Acute IE — develops suddenly and may become life threatening within days. Subacute or chronic IE (or subacute bacterial endocarditis) — develops slowly over a period of weeks to several months.

Does endocarditis go away?

Bacterial endocarditis is an infection of the heart’s inner lining or heart valves. It’s a serious condition that needs to be treated right away. Endocarditis can cause serious complications. It can also lead to death.

What is the most common cause of infective endocarditis?

Approximately 80% of infective endocarditis cases are caused by the bacteria streptococci and staphylococci. The third most common bacteria causing this disease is enterococci, and, like staphylococci, is commonly associated with healthcare-associated infective endocarditis.

Does endocarditis come back?

If your symptoms come back, call your doctor right away. You probably will need more antibiotics if testing shows that the bacteria were not completely destroyed. Some people who have endocarditis need surgery to repair or replace a heart valve or to prevent complications.

What antibiotic is used for endocarditis?

Treatment with aqueous penicillin or ceftriaxone is effective for most infections caused by streptococci. A combination of penicillin or ampicillin with gentamicin is appropriate for endocarditis caused by enterococci that are not highly resistant to penicillin.

How long is the treatment for endocarditis?

When endocarditis is caused by a bacterial infection, it usually is treated with four to six weeks of antibiotics. The type of antibiotic and the length of therapy depend on the results of the blood cultures. Antibiotic treatment is given intravenously (through a vein).

How is infective endocarditis diagnosed?

If your doctor suspects infective endocarditis, your blood will be tested for bacteria. A complete blood count (CBC) may also be used to check for anemia. A shortage of red blood cells can occur with infective endocarditis. Your doctor may order an echocardiogram, or an ultrasound of the heart.

What are the chances of surviving endocarditis?

Conclusions: Long term survival following infective endocarditis is 50% after 10 years and is predicted by early surgical treatment, age < 55 years, lack of congestive heart failure, and the initial presence of more symptoms of endocarditis.